Our flagship L-Solution platform is helping researchers unlock new insights into protein-protein and protein-ligand interactions through advanced electronic characterisation techniques.
Understanding Biomolecular Interactions
Characterising how proteins interact with other molecules is fundamental to drug discovery, diagnostics development, and basic biological research. Traditional methods often require fluorescent labels or surface immobilisation, which can alter the very interactions being studied.
The L-Solution takes a different approach — using label-free electronic detection to measure biomolecular binding events in their native state.
How It Works
The L-Solution platform monitors changes in electrical properties as biomolecules bind, fold, or interact at the sensor surface:
- Label-Free Detection: No fluorescent tags or radioactive markers needed
- Real-Time Kinetics: Watch binding events as they happen, not after the fact
- Native Conditions: Measurements in physiological buffers at controlled temperatures
- High Throughput: Process multiple samples in a single experimental run
Research Applications
Laboratories using the L-Solution have reported results across several key areas:
- Drug-Target Screening: Rapidly identify compounds that bind to therapeutic targets
- Antibody Characterisation: Measure binding affinity and specificity for diagnostic antibody development
- Protein Quality Control: Verify structural integrity of recombinant proteins
- DNA-Protein Interactions: Study transcription factor binding and gene regulation mechanisms
Collaboration with University of Malaya
The L-Solution was developed in collaboration with the University of Malaya's Department of Physics, combining decades of expertise in bioelectronics with practical laboratory instrumentation design. This partnership continues to drive improvements in sensitivity, reproducibility, and ease of use.
Learn More
The L-Solution platform is available for academic and commercial research laboratories. We offer full installation, training, and ongoing technical support. Get in touch to discuss how the L-Solution can advance your research programme.
